Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PPOX | P50336 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603144 | 0.92 | ALDH1A1 (0.62) | ALDH1A1TDP1L3MBTL1TSHRPPOX | |
| SCHEMBL8598336 | 0.91 | ALDH1A1 (0.57) | ALDH1A1TDP1L3MBTL1TSHRPPOX | |
| SCHEMBL7533766 | 0.89 | PPOX (0.56) | ALDH1A1TDP1L3MBTL1TSHRPPOX | |
| SCHEMBL8603307 | 0.83 | LMNA (0.65) | ALDH1A1TDP1L3MBTL1TSHRPPOX | |
| SCHEMBL8604315 | 0.81 | CSNK2A1 (0.49) | ALDH1A1PPOXGAAMAPTKDM4E | |
| SCHEMBL8603914 | 0.81 | CUL4A (0.39) | ALDH1A1TDP1L3MBTL1TSHRPPOX | |
| SCHEMBL8598548 | 0.80 | LMNA (0.46) | ALDH1A1TDP1L3MBTL1TSHRPPOX | |
| SCHEMBL8598863 | 0.80 | TSHR (0.47) | ALDH1A1TDP1L3MBTL1TSHRPPOX | |
| SCHEMBL8602970 | 0.80 | MAPT (0.46) | ALDH1A1TDP1L3MBTL1TSHRPPOX | |
| SCHEMBL8599242 | 0.79 | TDP1 (0.53) | ALDH1A1TDP1TSHRLMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |