Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 11/20 | 0.54 |
| ▸ | CTSB | P07858 | 11/20 | 0.54 |
| ▸ | CTSS | P25774 | 11/20 | 0.54 |
| ▸ | CTSK | P43235 | 11/20 | 0.54 |
| ▸ | NPPA | P01160 | 3/20 | 0.42 |
| ▸ | MME | P08473 | 3/20 | 0.42 |
| ▸ | TACR2 | P21452 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533061 | 0.90 | CTSS (0.56) | CTSLCTSBCTSSCTSKNPPA | |
| SCHEMBL7530187 | 0.90 | CTSS (0.57) | CTSLCTSBCTSSCTSKNPPA | |
| SCHEMBL7532290 | 0.89 | CTSS (0.58) | CTSLCTSBCTSSCTSKNPPA | |
| SCHEMBL7526705 | 0.89 | CTSS (0.55) | CTSLCTSBCTSSCTSKNPPA | |
| SCHEMBL7531164 | 0.89 | CTSS (0.54) | CTSLCTSBCTSSCTSKNPPA | |
| SCHEMBL7530137 | 0.89 | CTSS (0.62) | CTSLCTSBCTSSCTSKNPPA | |
| SCHEMBL7530008 | 0.89 | CTSK (0.63) | CTSLCTSBCTSSCTSKNPPA | |
| SCHEMBL7535486 | 0.87 | CTSS (0.53) | CTSLCTSBCTSSCTSKNPPA | |
| SCHEMBL7528445 | 0.86 | CTSS (0.74) | CTSLCTSBCTSSCTSKNPPA | |
| SCHEMBL7531006 | 0.86 | CTSS (0.50) | CTSLCTSBCTSSCTSKTACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |