Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.63 |
| ▸ | CTSL | P07711 | 12/20 | 0.63 |
| ▸ | CTSB | P07858 | 12/20 | 0.63 |
| ▸ | CTSS | P25774 | 12/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPPA | P01160 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530107 | 0.93 | CTSK (0.58) | CTSKCTSLCTSBCTSSKDM4E | |
| SCHEMBL7528445 | 0.91 | CTSS (0.74) | CTSKCTSLCTSBCTSSNPPA | |
| SCHEMBL7533061 | 0.90 | CTSS (0.56) | CTSKCTSLCTSBCTSSNPPA | |
| SCHEMBL7530187 | 0.90 | CTSS (0.57) | CTSKCTSLCTSBCTSSNPPA | |
| SCHEMBL7528076 | 0.90 | CTSL (0.54) | CTSKCTSLCTSBCTSSRAB9A | |
| SCHEMBL7526705 | 0.89 | CTSS (0.55) | CTSKCTSLCTSBCTSSNPPA | |
| SCHEMBL7532290 | 0.89 | CTSS (0.58) | CTSKCTSLCTSBCTSSNPPA | |
| SCHEMBL7531164 | 0.89 | CTSS (0.54) | CTSKCTSLCTSBCTSSNPPA | |
| SCHEMBL7533810 | 0.89 | CTSL (0.54) | CTSKCTSLCTSBCTSSNPPA | |
| SCHEMBL7530137 | 0.89 | CTSS (0.62) | CTSKCTSLCTSBCTSSNPPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | claimed |
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |