Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.58 |
| ▸ | CTSL | P07711 | 12/20 | 0.58 |
| ▸ | CTSB | P07858 | 12/20 | 0.58 |
| ▸ | CTSK | P43235 | 11/20 | 0.58 |
| ▸ | NPPA | P01160 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530137 | 0.93 | CTSS (0.62) | CTSSCTSLCTSBCTSKNPPA | |
| SCHEMBL7533061 | 0.91 | CTSS (0.56) | CTSSCTSLCTSBCTSKNPPA | |
| SCHEMBL7530187 | 0.91 | CTSS (0.57) | CTSSCTSLCTSBCTSKNPPA | |
| SCHEMBL7530384 | 0.90 | CTSL (0.47) | CTSSCTSLCTSBCTSKHPGD | |
| SCHEMBL7526705 | 0.90 | CTSS (0.55) | CTSSCTSLCTSBCTSKNPPA | |
| SCHEMBL7531164 | 0.90 | CTSS (0.54) | CTSSCTSLCTSBCTSKNPPA | |
| SCHEMBL7530008 | 0.89 | CTSK (0.63) | CTSSCTSLCTSBCTSKNPPA | |
| SCHEMBL7533810 | 0.89 | CTSL (0.54) | CTSSCTSLCTSBCTSKNPPA | |
| SCHEMBL7536001 | 0.89 | CTSL (0.55) | CTSSCTSLCTSBCTSKNPPA | |
| SCHEMBL7528445 | 0.88 | CTSS (0.74) | CTSSCTSLCTSBCTSKNPPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | claimed |
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |