Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534183 | 0.88 | HTR6 (0.56) | HTR6CA1CA2CA12CA9 | |
| SCHEMBL7171823 | 0.88 | HTR6 (0.62) | HTR6GAAGFERAPOBEC3GCA12 | |
| SCHEMBL7536397 | 0.87 | L3MBTL1 (0.44) | HTR6CA1CA2L3MBTL1LMNA | |
| SCHEMBL6089371 | 0.87 | CA1 (0.50) | CA1CA2L3MBTL1LMNAHTT | |
| SCHEMBL6086613 | 0.85 | CA1 (0.49) | HTR6CA1CA2L3MBTL1LMNA | |
| SCHEMBL6088076 | 0.85 | CA1 (0.49) | HTR6CA1CA2L3MBTL1LMNA | |
| SCHEMBL7536278 | 0.85 | MEN1 (0.51) | GAACA12CA9L3MBTL1LMNA | |
| SCHEMBL7540113 | 0.84 | L3MBTL1 (0.42) | HTR6CA1CA2L3MBTL1LMNA | |
| Batabulin SCHEMBL7103854 | 0.82 | LMNA (0.48) | HTR6CA1CA2L3MBTL1LMNA | |
| SCHEMBL6681264 | 0.82 | HTR6 (0.47) | HTR6CA1CA2GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020013496-A1 | Benzene compounds as antiproliferative and cholesterol lowering agents | AMGEN INC. | 2002-01-31 | — | — | US | claimed |
| EP-1005453-A1 | SUBSTITUTED BENZENE COMPOUNDS AS ANTIPROLIFERATIVE AND CHOLESTEROL LOWERING AGENTS | TULARIK, INC. (US) | 2000-06-07 | — | — | EP | claimed |
| WO-1999010320-A1 | SUBSTITUTED BENZENE COMPOUNDS AS ANTIPROLIFERATIVE AND CHOLESTEROL LOWERING AGENTS | TULARIK INC. (US) | 1999-03-04 | — | — | WO | claimed |
| CN-1247672-C | Transparent heat-absorbent plastic moulded material | BAYER AG (DE) | 2006-03-29 | — | — | CN | disclosed |
| CN-1484664-A | Transparent heat-absorbing plastic molding composition | — | 2004-03-24 | — | — | CN | disclosed |
| US-20020155296-A1 | Transparent plastics molding composition | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013496-A1 | Benzene compounds as antiproliferative and cholesterol lowering agents | CYP46A1, TGFB1, NR1H2 | HTR6 4459/4885CA1 4659/4885CA2 3895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.