Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CAD | P27708 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334770 | 0.86 | ALDH1A1 (0.46) | ALOX15ALDH1A1CADLMNAHSD17B10 | |
| SCHEMBL8018184 | 0.83 | ALOX15 (0.43) | ALOX15ALDH1A1CADCYP1A2LMNA | |
| SCHEMBL7522520 | 0.83 | ALOX15 (0.43) | ALOX15ALDH1A1CADCYP1A2LMNA | |
| SCHEMBL15526498 | 0.82 | ALOX15 (0.46) | ALOX15ALDH1A1CADLMNAHSD17B10 | |
| SCHEMBL4149915 | 0.80 | ALDH1A1 (0.44) | ALOX15ALDH1A1LMNAHSD17B10CPB2 | |
| SCHEMBL3212385 | 0.80 | ALDH1A1 (0.40) | ALOX15ALDH1A1LMNAHSD17B10CPB2 | |
| SCHEMBL7973384 | 0.78 | MGAM (0.41) | ALOX15ALDH1A1CADCYP1A2LMNA | |
| Hydrochloric Acid SCHEMBL7344003 | 0.78 | PIN1 (0.39) | ALOX15ALDH1A1LMNAHSD17B10CPB2 | |
| SCHEMBL7528046 | 0.77 | SMN1; SMN2 (0.39) | CA1CA2 | |
| SCHEMBL5153170 | 0.77 | CYP1A2 (0.40) | ALOX15ALDH1A1CYP1A2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100424-A | Process for the preparation of amino acetic acid esters with a tertiary hydrocarbon radical in the α-position | DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) | 2000-08-08 | — | — | US | claimed |
| US-6399809-B1 | FROM MALONIC ACID MONOESTER AMIDE | DEGUSSA AG (DE) | 2002-06-04 | — | — | US | disclosed |
| EP-0970944-B1 | Preparation of amino acetic acid esters substituted at position alpha by a tertiary hydrocarbon chain | DEGUSSA (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-6100424-A | Process for the preparation of amino acetic acid esters with a tertiary hydrocarbon radical in the α-position | DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) | 2000-08-08 | — | — | US | disclosed |
| EP-0970944-A1 | Preparation of amino acetic acid esters substituted at position alpha by a tertiary hydrocarbon chain | Degussa-Hüls Aktiengesellschaft (DE) | 2000-01-12 | — | — | EP | disclosed |