Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600065 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2CA14CA12CA1CA2 | |
| SCHEMBL27740042 | 0.79 | LMNA (0.35) | CA1CA2 | |
| SCHEMBL7208899 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2CA14CA12CA1CA2 | |
| SCHEMBL14827564 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2CA14CA12CA1CA2 | |
| SCHEMBL7534060 | 0.77 | ALOX15 (0.46) | CA1CA2 | |
| SCHEMBL526639 | 0.74 | DGAT1 (0.41) | SMN1; SMN2CA14CA12CA1CA2 | |
| SCHEMBL7973384 | 0.73 | MGAM (0.41) | SMN1; SMN2CA1CA2 | |
| SCHEMBL8408756 | 0.72 | ALDH1A1 (0.39) | CA1CA2KMT2A | |
| SCHEMBL28516660 | 0.71 | SMN1; SMN2 (0.35) | SMN1; SMN2CA14CA12CA1CA2 | |
| SCHEMBL9794475 | 0.70 | SMN1; SMN2 (0.40) | SMN1; SMN2CA14CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100424-A | Process for the preparation of amino acetic acid esters with a tertiary hydrocarbon radical in the α-position | DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) | 2000-08-08 | — | — | US | claimed |
| EP-0970944-B1 | Preparation of amino acetic acid esters substituted at position alpha by a tertiary hydrocarbon chain | DEGUSSA (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-6100424-A | Process for the preparation of amino acetic acid esters with a tertiary hydrocarbon radical in the α-position | DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) | 2000-08-08 | — | — | US | disclosed |
| EP-0970944-A1 | Preparation of amino acetic acid esters substituted at position alpha by a tertiary hydrocarbon chain | Degussa-Hüls Aktiengesellschaft (DE) | 2000-01-12 | — | — | EP | disclosed |