Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1444267 | 0.78 | GAA (0.61) | TSHRGAANPSR1POLBSMN1; SMN2 | |
| SCHEMBL9378048 | 0.77 | CHRM2 (0.31) | — | |
| SCHEMBL3023792 | 0.77 | — | — | |
| SCHEMBL10434839 | 0.75 | GAA (0.43) | TSHRCYP1A2CYP2C19CYP3A4GAA | |
| SCHEMBL10435028 | 0.74 | GAA (0.39) | TSHRCYP1A2CYP2C19CYP3A4GAA | |
| SCHEMBL23295 | 0.74 | PTGS2 (0.53) | CYP2C19GAAPOLBSMN1; SMN2PTGS2 | |
| SCHEMBL7476145 | 0.74 | GABRA1 (0.34) | SMN1; SMN2 | |
| SCHEMBL3167492 | 0.73 | PSEN1 (0.45) | CYP2C19GAANPSR1POLBSMN1; SMN2 | |
| SCHEMBL7328399 | 0.73 | ALDH1A1 (0.53) | POLBSMN1; SMN2ALOX15L3MBTL1LMNA | |
| SCHEMBL10434676 | 0.72 | GAA (0.50) | TSHRGAANPSR1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |