Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | EED | O75530 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708057 | 0.84 | KMT2A (0.69) | DRD2KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL6708055 | 0.84 | KMT2A (0.69) | DRD2KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL18541844 | 0.81 | ALDH1A1 (0.68) | DRD2KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL6068393 | 0.81 | ALDH1A1 (0.60) | DRD2KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL6070046 | 0.81 | KMT2A (0.60) | DRD2KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL6068390 | 0.81 | ALDH1A1 (0.60) | DRD2KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL6070052 | 0.81 | KMT2A (0.60) | DRD2KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL6069737 | 0.80 | KMT2A (0.52) | DRD2KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL6069745 | 0.80 | KMT2A (0.52) | DRD2KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL246627 | 0.80 | TSHR (0.63) | DRD2KMT2ALMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020013324-A1 | N-substituted imide derivatives with serotonergic activity | AMERICAN HOME PRODUCTS CORPORATION | 2002-01-31 | — | — | US | disclosed |
| EP-1157017-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6306859-B1 | PIPERIDINE ALKYL IMIDES AS NEUROTRANSMITTERS | AMERICAN HOME PRODUCTS CORPORATION | 2001-10-23 | — | — | US | disclosed |
| WO-2000052002-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |
| EP-0955296-A2 | Tertiary alkyl functionalized piperazine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-10 | — | — | EP | disclosed |
| US-4988814-A | Antidepressants and/or anxiolytic agents | AMERICAN HOME PRODUCTS CORP. (US) | 1991-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013324-A1 | N-substituted imide derivatives with serotonergic activity | TPH1, HTR1A, HTR1E | DRD2 43/4885KMT2A 1355/4885LMNA 1465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.