Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446129 | 0.83 | CYP1A2 (0.45) | L3MBTL1TDP1TAAR1TP53CYP2A6 | |
| SCHEMBL4929092 | 0.81 | CA1 (0.33) | CA2 | |
| SCHEMBL448811 | 0.78 | ALDH1A1 (0.42) | TSHRATMTDP1TAAR1CYP2A6 | |
| SCHEMBL7975652 | 0.75 | ALDH1A1 (0.41) | TSHRALDH1A1TAS1R3TAS1R1POLB | |
| SCHEMBL6546733 | 0.71 | TAAR1 (0.68) | L3MBTL1TSHRMAPK1ATMTDP1 | |
| SCHEMBL9332782 | 0.68 | TAAR1 (0.42) | L3MBTL1MAPK1TAAR1SMN1; SMN2 | |
| SCHEMBL36295 | 0.68 | TP53 (0.67) | L3MBTL1TSHRMAPK1ATMTDP1 | |
| SCHEMBL21138387 | 0.67 | TAAR1 (0.56) | L3MBTL1TSHRMAPK1ATMTDP1 | |
| SCHEMBL8953910 | 0.67 | IDO1 (0.45) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL327381 | 0.66 | TAAR1 (0.62) | L3MBTL1TAAR1TP53CYP2A6LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469115-B1 | ROOM TEMPERATURE VULCANIZABLE POLYISOBUTYLENE POLYMER HAVING HYDROLYZABLE SILYL- FUNCTIONAL GROUPS POSITIONED AT OR NEAR MOLECULAR CHAIN ENDS | DOW CORNING CORPORATION | 2002-10-22 | — | — | US | disclosed |
| WO-2002028924-A1 | SILYL-FUNCTIONAL PSEUDO-TELECHELIC POLYISOBUTYLENE TERPOLYMERS | DOW CORNING CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |
| WO-2001087999-A2 | VIRTUALLY TELECHELIC SILYL-FUNCTIONAL POLYISOBUTYLENE | DOW CORNING CORPORATION (US) | 2001-11-22 | — | — | WO | disclosed |
| US-6268451-B1 | POLYMERS OF ISOBUTYLENE, ISOPRENYLPHENYL AND VINYLPHENYL WITH SILYLALKYL GROUPS WITH SOLVENTS | UNIVERSITY OF MASSACHUSETTS LOWELL | 2001-07-31 | — | — | US | disclosed |