SCHEMBL7975652

SCHEMBL7975652

C=Cc1ccc(CC[SiH2]C(Cl)Cl)cc1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.32
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4929092 0.76 CA1 (0.33)
SCHEMBL1647493 0.75 ALDH1A1 (0.65) ALDH1A1TSHRTAS1R3TAS1R1POLB
SCHEMBL50012 0.75 ALDH1A1 (0.65) ALDH1A1TSHRTAS1R3TAS1R1POLB
SCHEMBL809721 0.75 ALDH1A1 (0.46) ALDH1A1TSHRTAS1R3TAS1R1POLB
SCHEMBL7534974 0.75 L3MBTL1 (0.45) ALDH1A1TSHRTAS1R3TAS1R1POLB
SCHEMBL446129 0.75 CYP1A2 (0.45) ALDH1A1
SCHEMBL448811 0.74 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL809974 0.72 ALDH1A1 (0.42) ALDH1A1TSHRTAS1R3TAS1R1POLB
SCHEMBL28390815 0.72 ALDH1A1 (0.42) ALDH1A1TSHRTAS1R3TAS1R1POLB
SCHEMBL810410 0.71 ALDH1A1 (0.52) ALDH1A1TSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268451-B1 POLYMERS OF ISOBUTYLENE, ISOPRENYLPHENYL AND VINYLPHENYL WITH SILYLALKYL GROUPS WITH SOLVENTS UNIVERSITY OF MASSACHUSETTS LOWELL 2001-07-31 US disclosed