SCHEMBL4929092

SCHEMBL4929092

ClCc1ccc(CC[SiH2]C(Cl)Cl)cc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL446129 0.81 CYP1A2 (0.45)
SCHEMBL7534974 0.81 L3MBTL1 (0.45) CA2
SCHEMBL448811 0.80 ALDH1A1 (0.42) CA1CA2
SCHEMBL7975652 0.76 ALDH1A1 (0.41)
SCHEMBL13658160 0.72 GFER (0.47) CA1CA2
SCHEMBL97582 0.69 CA1 (0.52) CA1CA2
SCHEMBL8953910 0.68 IDO1 (0.45)
SCHEMBL29156501 0.68 CA1 (0.32) CA1CA2
SCHEMBL9192375 0.68 CA2 (0.42) CA1CA2
SCHEMBL12401893 0.68 HTR2A (0.44) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080125549-A1 COUPLING OF LIVING CARBOCATIONIC POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2008-05-29 US disclosed
EP-1177219-A1 LIVING CATIONIC POLYMERS PREPARED FROM SILYL-FUNCTIONAL AROMATIC INITIATORS DOW CORNING CORPORATION (US) 2002-02-06 EP disclosed
US-6194597-B1 REACTING CATIONICALLY POLYMERIZABLE MONOMER(ISOBUTYLENE, ISOPRENE) WITH SILYL GROUP CONTAINING INITIATOR IN PRESENCE OF LEWIS ACID TO FORM LIVING CATIONIC POLYMER CONTAINING SILIY GROUPS DOW CORNING CORPORATION 2001-02-27 US disclosed
WO-2000063256-A1 LIVING CATIONIC POLYMERS PREPARED FROM SILYL-FUNCTIONAL AROMATIC INITIATORS DOW CORNING CORPORATION (US) 2000-10-26 WO disclosed