SCHEMBL753524

SCHEMBL753524

ON=Cc1ncccc1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGF23 Q9GZV9 2/20 0.41
HPGD P15428 2/20 0.39
GFER P55789 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GSK3A P49840 1/20 0.37
GSK3B P49841 1/20 0.37
GRIN2D O15399 2/20 0.37
GRIN3B O60391 2/20 0.37
GRIN1 Q05586 2/20 0.37
GRIN2A Q12879 2/20 0.37
GRIN2B Q13224 2/20 0.37
GRIN2C Q14957 2/20 0.37
GRIN3A Q8TCU5 2/20 0.37
TOP1 P11387 1/20 0.37
MAPT P10636 1/20 0.36
CYP2A6 P11509 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 2/20 0.36
CYP3A4 P08684 2/20 0.36
CHRNB2 P17787 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21645885 1.00 FGF23 (0.41) FGF23HPGDGFERSMN1; SMN2GSK3A
SCHEMBL10580559 1.00 FGF23 (0.41) FGF23HPGDGFERSMN1; SMN2GSK3A
SCHEMBL28187102 0.82 PTGS1 (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11178888 0.79 PTGS2 (0.41) HPGDSMN1; SMN2MAPTALDH1A1HSD17B10
SCHEMBL30019890 0.77 TOP1 (0.41) HPGDTOP1MAPTCYP2A6ALDH1A1
SCHEMBL2083077 0.76 ALDH1A1 (0.42) HPGDTOP1MAPTCYP2A6ALDH1A1
SCHEMBL10824239 0.76 TOP1 (0.40) HPGDSMN1; SMN2TOP1MAPTCYP2A6
Iodide SCHEMBL27658785 0.74 TOP1 (0.39) HPGDSMN1; SMN2TOP1MAPTCYP2A6
SCHEMBL9000310 0.74 TOP1 (0.42) SMN1; SMN2TOP1MAPTALDH1A1HSD17B10
SCHEMBL16712006 0.73 FGF23 (0.45) FGF23HPGDSMN1; SMN2MAPTCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466836-A Method for synthesizing allyl tertiary amine 万华化学集团股份有限公司 2024-01-30 CN claimed
CN-113522048-B Oil-water separation membrane based on oxime carbamate bond, preparation method and application thereof 陕西科技大学 2022-07-01 CN claimed
EP-3915549-A1 SENESCENCE INDUCERS FOR USE IN THE TREATMENT AND/OR PREVENTION OF VIRUS INDUCED DISEASES Merck Patent GmbH (DE) 2021-12-01 EP claimed
CN-113522048-A Oil-water separation membrane based on oxime carbamate bond, preparation method and application thereof 陕西科技大学 2021-10-22 CN claimed
CN-103833561-B The N-arylation method of alkane amine HENGYANG NORMAL UNIVERSITY (CN) 2016-01-13 CN claimed
CN-103833561-A Method for N-arylation of alkane amine UNIV HENGYANG NORMAL 2014-06-04 CN claimed
US-5320969-A Measuring the change in color when complexing a metal compound and colored indicator in a buffered solution of biological sample, e.g. urine MILES INC. (US) 1994-06-14 US claimed
CN-117466836-A Method for synthesizing allyl tertiary amine 万华化学集团股份有限公司 2024-01-30 CN disclosed
US-20230416837-A1 COMPOSITIONS AND METHODS FOR IDENTIFICATION, ASSESSMENT AND TREATMENT OF CANCER PATIENT NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-12-28 US disclosed
EP-4244390-A1 COMPOSITIONS AND METHODS FOR IDENTIFICATION, ASSESSMENT AND TREATMENT OF CANCER PATIENT Ambay Immune Sensors and Controls, LLC/Ambay (US) 2023-09-20 EP disclosed
CN-113522048-B Oil-water separation membrane based on oxime carbamate bond, preparation method and application thereof 陕西科技大学 2022-07-01 CN disclosed
WO-2022104258-A1 COMPOSITIONS AND METHODS FOR IDENTIFICATION, ASSESSMENT AND TREATMENT OF CANCER PATIENT AMBAY IMMUNE SENSORS AND CONTROLS, LLC/AMBAY (US) 2022-05-19 WO disclosed
EP-3915549-A1 SENESCENCE INDUCERS FOR USE IN THE TREATMENT AND/OR PREVENTION OF VIRUS INDUCED DISEASES Merck Patent GmbH (DE) 2021-12-01 EP disclosed
US-4876232-A PHENANTHROLINE ON CARBON OR CHARCOAL SUPPORT Macedo, Pedro B. (US) 1989-10-24 US disclosed
EP-0335971-A1 SUPPORTED HETEROPOLYCYCLIC COMPOUNDS IN THE SEPARATION AND REMOVAL OF LATE TRANSITION METALS MACEDO, Pedro B. (US) 1989-10-11 EP disclosed
EP-0335971-A4 SUPPORTED HETEROPOLYCYCLIC COMPOUNDS IN THE SEPARATION AND REMOVAL OF LATE TRANSITION METALS. MACEDO PEDRO B (US) 1989-09-11 EP disclosed
WO-1989003434-A1 SUPPORTED HETEROPOLYCYCLIC COMPOUNDS IN THE SEPARATION AND REMOVAL OF LATE TRANSITION METALS MACEDO, PEDRO, B. (US) 1989-04-20 WO disclosed
EP-0283777-A1 Benzaldoxime derivatives BAYER AG (DE) 1988-09-28 EP disclosed
US-4742070-A Arylsulphonyl-pyridinealdoxime derivatives, useful as fungicides BAYER AKTIENGESELLSCHAFT (DE) 1988-05-03 US disclosed
EP-0236897-A1 Arylsulfonyl-pyridinealdoxime derivatives BAYER AG (DE) 1987-09-16 EP disclosed