Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852429 | 0.89 | KIF11 (0.38) | ALDH1A1MAPK1MAPTKIF11LMNA | |
| SCHEMBL5832056 | 0.83 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPK1CES1KCNN4 | |
| SCHEMBL31601269 | 0.82 | GSK3B (0.33) | ALDH1A1MAPK1CYP3A4KMT2AMAPT | |
| SCHEMBL13166557 | 0.82 | MAPK1 (0.41) | ALDH1A1ALOX15MAPK1CES1KCNN4 | |
| SCHEMBL16673523 | 0.80 | MAPK1 (0.40) | ALDH1A1ALOX15MAPK1CES1KCNN4 | |
| SCHEMBL15063659 | 0.78 | KCNN4 (0.44) | ALDH1A1ALOX15MAPK1CES1KCNN4 | |
| SCHEMBL8314455 | 0.77 | MAPK1 (0.44) | ALDH1A1ALOX15MAPK1CES1KCNN4 | |
| SCHEMBL1774346 | 0.77 | MAPK1 (0.44) | ALDH1A1ALOX15MAPK1CES1KCNN4 | |
| SCHEMBL28237952 | 0.75 | MAPK1 (0.43) | ALDH1A1ALOX15MAPK1CES1KCNN4 | |
| SCHEMBL487150 | 0.75 | MAPK1 (0.43) | ALDH1A1ALOX15MAPK1CES1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2189452-B1 | ASCORBIC ACID DERIVATIVES AND SALTS THEREOF, PROCESS FOR THEIR PRODUCTION, AND COSMETIC PREPARATIONS THEREOF | SEIWA KASEI CO LTD (JP) | 2012-11-21 | — | — | EP | disclosed |
| EP-0937719-B1 | Process for the preparation of CIS-isoambrettoldide and her application | SYNAROME (FR) | 2002-04-10 | — | — | EP | disclosed |
| EP-0937719-A1 | Process for the preparation of CIS-isoambrettoldide and her application | Synarome (FR) | 1999-08-25 | — | — | EP | disclosed |