SCHEMBL7535702

SCHEMBL7535702

O=Cc1ccc(S(=O)(=O)Oc2c(Cl)ccc3ccccc23)c2ccccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.35
ERN1 O75460 2/20 0.35
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33
TUBB3 Q13509 1/20 0.33
TUBB2A Q13885 1/20 0.33
TUBB8 Q3ZCM7 1/20 0.33
TUBA3E Q6PEY2 1/20 0.33
TUBA1A Q71U36 1/20 0.33
TUBA1C Q9BQE3 1/20 0.33
TUBB6 Q9BUF5 1/20 0.33
TUBB2B Q9BVA1 1/20 0.33
TUBB1 Q9H4B7 1/20 0.33
MAPT P10636 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7543592 0.82 LDHA (0.46) CYP2A6ERN1POLBMEN1KMT2A
SCHEMBL7205025 0.79 ALDH1A1 (0.44) ERN1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL7545228 0.79 NR4A1 (0.45) MAPTPOLBMEN1KMT2AALDH1A1
SCHEMBL7538432 0.76 TUBB4A (0.46) CYP2A6ERN1TUBB4ATUBBTUBA3C
SCHEMBL7538519 0.75 ALDH1A1 (0.41) MAPTCYP1A2CYP2C19POLBMEN1
SCHEMBL7541849 0.70 TUBB4A (0.48) CYP2A6TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL7541893 0.70 IDO1 (0.37) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL7540797 0.69 ALDH1A1 (0.40) CYP2A6ERN1POLBMEN1KMT2A
SCHEMBL9669203 0.69 CYP2A6 (0.54) CYP2A6ERN1MAPTCYP1A2CYP2C9
SCHEMBL1254074 0.68 CYP2A6 (0.59) CYP2A6CYP1A2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 CYP2A6 1575/4885ERN1 4751/4885TUBB4A 1041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.