Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 7/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7533946 | 0.89 | ALDH1A1 (0.42) | TPH1PPARGPPARAGPR142 | |
| SCHEMBL7535596 | 0.74 | ITGA4 (0.48) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL22189982 | 0.74 | SLC7A5 (0.61) | TPH1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL22189984 | 0.74 | SLC7A5 (0.61) | TPH1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL7227087 | 0.72 | ITGB1 (0.56) | TPH1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL5162726 | 0.72 | ITGB1 (0.56) | TPH1SLC7A5ALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL7419313 | 0.71 | ALDH1A1 (0.42) | TPH1PPARGPPARAGPR142 | |
| SCHEMBL7416021 | 0.71 | GPR142 (0.40) | PPARGPPARAGPR142 | |
| SCHEMBL6168594 | 0.71 | TPH1 (0.68) | TPH1SLC7A5ALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL5159881 | 0.71 | ITGB1 (0.55) | TPH1SLC7A5ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002008202-A2 | ALPHA AMINO ACID DERIVATIVES--INHIBITORS OF LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-31 | — | — | WO | disclosed |