SCHEMBL7535989

SCHEMBL7535989

N#CC=C(C#N)c1nccs1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.45
ALDH1A1 P00352 4/20 0.41
RAB9A P51151 5/20 0.36
NPC1 O15118 3/20 0.36
JAK3 P52333 1/20 0.34
POLB P06746 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.31
NOS1 P29475 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PKM P14618 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16533076 0.83 ALDH1A1 (0.47) FTOALDH1A1RAB9ANPC1JAK3
SCHEMBL13369309 0.79 ALDH1A1 (0.52) FTOALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL7192578 0.77 FTO (0.42) FTOALDH1A1RAB9ANPC1JAK3
SCHEMBL15657999 0.77 FTO (0.42) FTOALDH1A1RAB9ANPC1JAK3
SCHEMBL14682592 0.77 FTO (0.42) FTOALDH1A1RAB9ANPC1JAK3
SCHEMBL15658000 0.77 FTO (0.42) FTOALDH1A1RAB9ANPC1JAK3
SCHEMBL16532962 0.76 FTO (0.47) FTOALDH1A1RAB9ANPC1JAK3
SCHEMBL7688372 0.75 NPC1 (0.56) FTOALDH1A1RAB9ANPC1JAK3
SCHEMBL5141220 0.75 FTO (0.41) FTOALDH1A1RAB9ANPC1JAK3
SCHEMBL13369212 0.74 ALDH1A1 (0.42) FTOALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524637-B1 Mixture of dyes for cyan dye donor for thermal color proofing EASTMAN KODAK CO (US) 1996-03-06 EP claimed
EP-0524637-A1 Mixture of dyes for cyan dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1993-01-27 EP claimed
US-5177052-A MIXTURE OF DYES FOR CYAN DYE DONOR FOR THERMAL COLOR PROOFING EASTMAN KODAK COMPANY (US) 1993-01-05 US claimed
EP-0771672-B1 Laser recording method EASTMAN KODAK CO (US) 2002-05-15 EP disclosed
US-5674661-A IMAGEWISE LASER EXPOSURE OF SINGLE SHEET RECORDING ELEMENT HAVING CRYSTALLIZATION RESISTANT DISAZO CYAN DYE DISPERSED IN POLYMERIC BINDER EASTMAN KODAK COMPANY (US) 1997-10-07 US disclosed
EP-0771672-A2 Laser recording element EASTMAN KODAK COMPANY (US) 1997-05-07 EP disclosed
EP-0636492-B1 Use of mixture of dyes for black laser ablative recording element EASTMAN KODAK CO (US) 1997-03-26 EP disclosed
US-5503956-A DISPERSING AN INFRARED-ABSORBING MIXTURE OF AT LEAST ONE CYAN, MAGENTA AND YELLOW DYE IN POLYMERIC BINDER EASTMAN KODAK COMPANY (US) 1996-04-02 US disclosed
EP-0524637-B1 Mixture of dyes for cyan dye donor for thermal color proofing EASTMAN KODAK CO (US) 1996-03-06 EP disclosed
EP-0511625-B1 Mixture of yellow and cyan dyes to form a green hue for color filter array element EASTMAN KODAK CO (US) 1995-10-11 EP disclosed
EP-0518349-B1 Mixture of cyan and yellow dyes to form a green hue for color filter array element EASTMAN KODAK CO (US) 1995-08-30 EP disclosed
US-5177052-A MIXTURE OF DYES FOR CYAN DYE DONOR FOR THERMAL COLOR PROOFING EASTMAN KODAK COMPANY (US) 1993-01-05 US disclosed
EP-0518349-A1 Mixture of cyan and yellow dyes to form a green hue for color filter array element EASTMAN KODAK COMPANY (US) 1992-12-16 EP disclosed
US-5168094-A Thermal printing EASTMAN KODAK COMPANY (US) 1992-12-01 US disclosed
EP-0511625-A1 Mixture of yellow and cyan dyes to form a green hue for color filter array element EASTMAN KODAK COMPANY (US) 1992-11-04 EP disclosed
US-5147844-A Polymeric image receiving layer, having a thermally transferred image of a repeating pattern thereon, on a support EASTMAN KODAK COMPANY (US) 1992-09-15 US disclosed
EP-0486995-A1 Mixture of dyes for magenta dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1992-05-27 EP disclosed
EP-0483800-A1 Mixture of dyes for magenta dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1992-05-06 EP disclosed
US-5061676-A Mixture of dyes for magenta dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1991-10-29 US disclosed
US-5023229-A Mixture of dyes for magenta dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1991-06-11 US disclosed