Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.52 |
| ▸ | DRD2 | P14416 | 9/20 | 0.47 |
| ▸ | HTR2A | P28223 | 7/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.47 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.47 |
| ▸ | DRD1 | P21728 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.47 |
| ▸ | HRH1 | P35367 | 4/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13393404 | 0.93 | KDM1A (0.50) | KDM1ADRD2HTR2ACHRM1KCNH2 | |
| SCHEMBL13305145 | 0.88 | KDM1A (0.64) | KDM1ADRD2HTR2ACHRM1KCNH2 | |
| SCHEMBL13305239 | 0.86 | KDM1A (0.60) | KDM1ADRD2HTR2ACHRM1KCNH2 | |
| SCHEMBL7529841 | 0.85 | KDM1A (0.52) | KDM1ADRD2HTR2ACHRM1KCNH2 | |
| SCHEMBL13305459 | 0.85 | FPR2 (0.66) | KDM1ADRD2HTR2ACHRM1KCNH2 | |
| SCHEMBL13393383 | 0.84 | KDM1A (0.51) | KDM1ADRD2HTR1AADRA1ASMN1; SMN2 | |
| SCHEMBL13305365 | 0.82 | HTR1A (0.50) | KDM1ADRD2HTR2ACHRM1KCNH2 | |
| SCHEMBL7536360 | 0.81 | KDM1A (0.52) | KDM1ADRD2HTR2ACHRM1KCNH2 | |
| SCHEMBL5807070 | 0.79 | DRD2 (0.53) | DRD2HTR2AKCNH2HTR1ASLC6A4 | |
| SCHEMBL7533558 | 0.78 | KDM1A (0.78) | KDM1ADRD2HTR2ACHRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022130-A2 | MEANS FOR REGULATING IMMUNE DEFENCES | INSTITUT NECKER (FR) | 2002-03-21 | — | — | WO | disclosed |