Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.52 |
| ▸ | DRD2 | P14416 | 8/20 | 0.46 |
| ▸ | HTR2A | P28223 | 7/20 | 0.46 |
| ▸ | HTR1A | P08908 | 6/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.46 |
| ▸ | DRD3 | P35462 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.46 |
| ▸ | DRD1 | P21728 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.46 |
| ▸ | HRH1 | P35367 | 5/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529841 | 0.93 | KDM1A (0.52) | KDM1ADRD2HTR2AHTR1ACHRM1 | |
| SCHEMBL13305145 | 0.88 | KDM1A (0.64) | KDM1ADRD2HTR2AHTR1ACHRM1 | |
| SCHEMBL13305239 | 0.86 | KDM1A (0.60) | KDM1ADRD2HTR2AHTR1ACHRM1 | |
| SCHEMBL7535997 | 0.81 | KDM1A (0.52) | KDM1ADRD2HTR2AHTR1ACHRM1 | |
| SCHEMBL7594811 | 0.78 | KDM1A (0.78) | KDM1ADRD2HTR2AHTR1ACHRM1 | |
| SCHEMBL13305459 | 0.78 | FPR2 (0.66) | KDM1ADRD2HTR2AHTR1ACHRM1 | |
| SCHEMBL282769 | 0.77 | CHRM1 (0.53) | DRD2HTR2AHTR1ACHRM1DRD3 | |
| SCHEMBL13305365 | 0.77 | HTR1A (0.50) | KDM1ADRD2HTR2AHTR1ACHRM1 | |
| SCHEMBL6102599 | 0.77 | CACNA1B (0.51) | KDM1ADRD2HTR2AHTR1ACHRM1 | |
| SCHEMBL6969785 | 0.76 | CACNA1B (0.50) | KDM1ADRD2HTR2AHTR1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022130-A2 | MEANS FOR REGULATING IMMUNE DEFENCES | INSTITUT NECKER (FR) | 2002-03-21 | — | — | WO | disclosed |