Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538929 | 0.88 | AOC3 (0.37) | LMNAITGB3ITGA2BKMT2A | |
| Hydrochloric Acid SCHEMBL7538675 | 0.86 | FKBP1A (0.43) | GAAHRH3L3MBTL1KMT2A | |
| SCHEMBL7544912 | 0.84 | CYP4A11 (0.38) | LMNAKMT2ACA2 | |
| SCHEMBL8325473 | 0.84 | FFAR1 (0.44) | FFAR1ITGB3ITGA2BKEAP1FFAR4 | |
| SCHEMBL7540020 | 0.83 | FKBP1A (0.55) | KMT2A | |
| SCHEMBL7536716 | 0.83 | KMT2A (0.33) | KMT2A | |
| SCHEMBL7538015 | 0.81 | FKBP1A (0.32) | KMT2A | |
| SCHEMBL5717885 | 0.80 | SIGMAR1 (0.45) | KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL5849112 | 0.79 | SIGMAR1 (0.44) | KMT2AHSD17B10 | |
| SCHEMBL8930521 | 0.76 | GFER (0.36) | L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211249-A1 | NOVEL THIAZINE OR PYRAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-05 | — | — | EP | disclosed |