Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379431 | 0.84 | SIGMAR1 (0.51) | SIGMAR1OPRM1OPRD1OPRK1USP2 | |
| SCHEMBL7536787 | 0.84 | FFAR1 (0.41) | FFAR1KEAP1FFAR4ITGB3ITGA2B | |
| SCHEMBL4299855 | 0.76 | SIGMAR1 (0.42) | SIGMAR1OPRM1OPRD1OPRK1USP2 | |
| SCHEMBL7538929 | 0.72 | AOC3 (0.37) | ITGB3ITGA2BALDH1A1 | |
| Phenyl Propionic Acid SCHEMBL5057672 | 0.72 | KEAP1 (0.76) | FFAR1KEAP1FFAR4ADRA1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7538675 | 0.71 | FKBP1A (0.43) | ALDH1A1TSHR | |
| SCHEMBL2302994 | 0.70 | ITGB3 (0.61) | FFAR1KEAP1SIGMAR1FFAR4ITGB3 | |
| SCHEMBL10900445 | 0.70 | KCNH2 (0.57) | FFAR1KEAP1SIGMAR1ITGB3ITGA2B | |
| SCHEMBL5717885 | 0.68 | SIGMAR1 (0.45) | SIGMAR1OPRM1OPRD1USP2ALDH1A1 | |
| SCHEMBL7544912 | 0.68 | CYP4A11 (0.38) | SIGMAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912175-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-09-08 | — | — | EP | disclosed |
| EP-0912175-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998000134-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1998-01-08 | — | — | WO | disclosed |