Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | MLNR | O43193 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7536787 | 0.84 | FFAR1 (0.41) | CA2KMT2ALMNA | |
| SCHEMBL7538929 | 0.83 | AOC3 (0.37) | KMT2AMAPKAPK2LMNAAOC3 | |
| SCHEMBL7536716 | 0.83 | KMT2A (0.33) | KMT2AMAPKAPK2AOC3KCNJ1KCNH2 | |
| Hydrochloric Acid SCHEMBL7538675 | 0.81 | FKBP1A (0.43) | KMT2AKCNH2 | |
| SCHEMBL7540020 | 0.78 | FKBP1A (0.55) | KMT2A | |
| SCHEMBL5717885 | 0.77 | SIGMAR1 (0.45) | SIGMAR1KMT2A | |
| SCHEMBL8930521 | 0.76 | GFER (0.36) | SIGMAR1KMT2AMAPKAPK2 | |
| Hydrochloric Acid SCHEMBL5849112 | 0.76 | SIGMAR1 (0.44) | SIGMAR1KMT2A | |
| SCHEMBL7538015 | 0.76 | FKBP1A (0.32) | KMT2A | |
| SCHEMBL8930545 | 0.72 | ADRB1 (0.49) | KMT2ALMNAKCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211249-A1 | NOVEL THIAZINE OR PYRAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-05 | — | — | EP | disclosed |