Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.34 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BBOX1 | O75936 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL7536805 | 0.96 | SLC22A16 (0.45) | SLC22A16MAPTCPT2CPT1AGALR3 | |
| Pivalate SCHEMBL17025968 | 0.88 | SLC22A16 (0.39) | SLC22A16MAPTCPT2CPT1AGALR3 | |
| Acrylamide SCHEMBL27953686 | 0.84 | MAPT (0.46) | SLC22A16MAPTCPT2CPT1AGALR3 | |
| Acetic Acid SCHEMBL11505398 | 0.83 | SLC22A16 (0.52) | SLC22A16MAPTCPT2CPT1AGALR3 | |
| Bicarbonate SCHEMBL28323257 | 0.83 | SLC22A16 (0.56) | SLC22A16MAPTCPT2CPT1AGALR3 | |
| Acrylic Acid SCHEMBL7536810 | 0.82 | MAPT (0.42) | SLC22A16MAPTCPT2CPT1AGALR3 | |
| Carbamic Acid SCHEMBL11505008 | 0.81 | MAPT (0.50) | SLC22A16MAPTCPT2CPT1AGALR3 | |
| Bicarbonate SCHEMBL8320369 | 0.81 | SLC22A16 (0.54) | SLC22A16MAPTCPT2CPT1AGALR3 | |
| Acetic Acid SCHEMBL5670671 | 0.81 | SLC22A16 (0.54) | SLC22A16MAPTCPT2CPT1AGALR3 | |
| Acetic Acid SCHEMBL11505402 | 0.79 | SLC22A16 (0.52) | SLC22A16MAPTCPT2CPT1AGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020111395-A1 | Ink, ink cartridge storing said ink and recording device using said ink | FUJI PHOTO FILM CO. LTD. (JP) | 2002-08-15 | — | — | US | disclosed |
| EP-0302939-B1 | TONER FOR DEVELOPING ELECTROSTATICALLY CHARGED IMAGE | NIPPON CARBIDE KOGYO KK (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-4996127-A | Particles of anionic or cationic polymers, coloring agent and optional charge controlling agent | NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) | 1991-02-26 | — | — | US | disclosed |
| EP-0302939-A1 | TONER FOR DEVELOPING ELECTROSTATICALLY CHARGED IMAGE | NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) | 1989-02-15 | — | — | EP | disclosed |