Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537026 | 1.00 | L3MBTL1 (0.39) | L3MBTL1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL8374758 | 0.80 | CES2 (0.48) | GAACES2CES1LMNA | |
| SCHEMBL7481245 | 0.70 | GAA (0.55) | NPC1RAB9AGAACYP2D6CYP2C9 | |
| SCHEMBL27138142 | 0.67 | DGAT1 (0.33) | NPC1RAB9ACES2CES1 | |
| SCHEMBL27007958 | 0.67 | DGAT1 (0.33) | NPC1RAB9ACES2CES1 | |
| SCHEMBL10332608 | 0.67 | CES2 (0.46) | GAACES2CES1LMNA | |
| SCHEMBL5775733 | 0.67 | CES2 (0.46) | GAACES2CES1LMNA | |
| SCHEMBL20136432 | 0.67 | CES2 (0.46) | GAACES2CES1LMNA | |
| SCHEMBL2284506 | 0.66 | CES2 (0.46) | NPC1RAB9ACES2CES1LMNA | |
| SCHEMBL12377007 | 0.66 | CES2 (0.46) | NPC1RAB9ACES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187818-A1 | PESTICIDALLY ACTIVE TETRAZINE DERIVATIVES | Syngenta Participations AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000078739-A1 | PESTICIDALLY ACTIVE TETRAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-12-28 | — | — | WO | disclosed |