Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29676897 | 1.00 | NAAA (0.40) | NAAAEPHX1CYP19A1NR1H4GAA | |
| SCHEMBL3516768 | 1.00 | NAAA (0.40) | NAAAEPHX1CYP19A1NR1H4GAA | |
| SCHEMBL21614507 | 0.98 | NAAA (0.39) | NAAAEPHX1CYP19A1NR1H4GAA | |
| Ethane SCHEMBL28092403 | 0.85 | EPHX1 (0.47) | NAAAEPHX1CYP19A1HTTNPC1 | |
| SCHEMBL7539573 | 0.84 | EPHX1 (0.48) | NAAAEPHX1CYP19A1HTTSMN1; SMN2 | |
| SCHEMBL22092280 | 0.84 | EPHX1 (0.48) | NAAAEPHX1CYP19A1HTTSMN1; SMN2 | |
| SCHEMBL780366 | 0.84 | EPHX1 (0.48) | NAAAEPHX1CYP19A1HTTSMN1; SMN2 | |
| SCHEMBL8101682 | 0.84 | EPHX1 (0.48) | NAAAEPHX1CYP19A1HTTSMN1; SMN2 | |
| SCHEMBL8101691 | 0.84 | EPHX1 (0.48) | NAAAEPHX1CYP19A1HTTSMN1; SMN2 | |
| SCHEMBL10386170 | 0.84 | EPHX1 (0.48) | NAAAEPHX1CYP19A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240010606-A1 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | SITRYX THERAPEUTICS LIMITED (GB) | 2024-01-11 | — | — | US | disclosed |
| EP-4200275-A2 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | Sitryx Therapeutics Limited (GB) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022038365-A9 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022038365-A2 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2022-02-24 | — | — | WO | disclosed |
| US-20020190818-A1 | High frequency band pass filter | TDK CORPORATION (JP) | 2002-12-19 | — | — | US | disclosed |
| EP-0788118-B1 | Low dielectric polymer and film, substrate and electronic part using the same | TDK CORP (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5914283-A | FUMARIC ACID DIESTER MONOMER-CONTAINING POLYMER FILM; HEAT RESISTANCE, WEATHER RESISTANCE | TDK CORPORATION (JP) | 1999-06-22 | — | — | US | disclosed |
| EP-0722959-B1 | Highly oxygen-permeable heat-resistant material | MENICON CO LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| EP-0788118-A1 | Low dielectric polymer and film, substrate and electronic part using the same | TDK Corporation (JP) | 1997-08-06 | — | — | EP | disclosed |
| EP-0722959-A2 | Highly oxygen-permeable heat-resistant material | Menicon Co., Ltd. (JP) | 1996-07-24 | — | — | EP | disclosed |
| EP-0524557-B1 | Ocular lens material | MENICON CO LTD (JP) | 1996-01-17 | — | — | EP | disclosed |
| US-5391591-A | A curable additional copolymer molding materials having a styrenic monomer, a hydrophilic acrylamide monomer and a crosslinkable vinylbenzyl acrylate monomer; permselectivity, tensile strength, low water absorption | MENICON CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5250583-A | Polymer of fluoroalkyl silicon-containing alkyl fumarate, N-vinyllactam, acrylic or methacrylic acid, crosslinkable monomer | MENICON CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0524557-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1993-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240010606-A1 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | FH, SUCNR1, ARG2 | NAAA 3153/4885EPHX1 1163/4885CYP19A1 278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.