Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537213 | 0.89 | ACLY (0.53) | ACLYNPSR1TSHRLMNAHPGD | |
| SCHEMBL8214778 | 0.85 | NPSR1 (0.47) | ACLYNPSR1TSHRLMNAHPGD | |
| SCHEMBL532975 | 0.82 | ACLY (0.69) | ACLYNPSR1TSHRLMNAHPGD | |
| SCHEMBL7532543 | 0.82 | KAT6A (0.53) | ACLYTSHRLMNAHPGDIKBKB | |
| SCHEMBL7537211 | 0.81 | KMT2A (0.55) | ACLYNPSR1HPGDKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL533067 | 0.81 | ACLY (0.68) | ACLYNPSR1TSHRLMNAHPGD | |
| SCHEMBL7532972 | 0.80 | ACLY (0.47) | ACLYTSHRLMNAHPGDKDM4E | |
| SCHEMBL3657767 | 0.80 | ACLY (0.55) | ACLYNPSR1TSHRLMNAHPGD | |
| SCHEMBL7537970 | 0.78 | ACLY (0.50) | ACLYNPSR1TSHRLMNAHPGD | |
| SCHEMBL7533711 | 0.78 | LMNA (0.49) | ACLYTSHRLMNAHPGDPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |