Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | PHGDH | O43175 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533940 | 0.90 | RAB9A (0.56) | KMT2AMEN1CASP3SENP8SENP7 | |
| SCHEMBL7533552 | 0.87 | NR1H3 (0.57) | KMT2AMEN1CASP3SENP8SENP7 | |
| SCHEMBL7569195 | 0.86 | MEN1 (0.49) | KMT2AMEN1CASP3SENP8SENP7 | |
| SCHEMBL7533623 | 0.85 | ACLY (0.55) | KMT2AMEN1NPSR1HPGDALDH1A1 | |
| SCHEMBL7532028 | 0.85 | ADORA3 (0.53) | KMT2AMEN1PHGDHCA12CA9 | |
| SCHEMBL7538859 | 0.83 | ACLY (0.53) | KMT2AMEN1CASP3SENP8SENP7 | |
| SCHEMBL3972622 | 0.83 | CASP3 (0.50) | KMT2AMEN1CASP3SENP8SENP7 | |
| SCHEMBL7534407 | 0.82 | LMNA (0.56) | KMT2AMEN1CASP3SENP8SENP7 | |
| SCHEMBL7537207 | 0.81 | ACLY (0.53) | KMT2AMEN1NPSR1HPGDPOLB | |
| SCHEMBL7537213 | 0.81 | ACLY (0.53) | KMT2AMEN1NPSR1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |