Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.55 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL27763924 | 0.73 | CES2 (0.57) | CES2CES1L3MBTL1NPC1 | |
| SCHEMBL1531080 | 0.72 | CES2 (0.68) | CES2CES1L3MBTL1SNCANPC1 | |
| SCHEMBL8070666 | 0.72 | CES2 (1.00) | CES2CES1L3MBTL1SNCANPC1 | |
| SCHEMBL13291390 | 0.72 | CES2 (0.74) | CES2CES1L3MBTL1SNCANPC1 | |
| SCHEMBL2834785 | 0.71 | CES2 (0.55) | CES2CES1L3MBTL1RAB9A | |
| SCHEMBL6990872 | 0.71 | CES2 (0.65) | CES2CES1L3MBTL1SNCA | |
| SCHEMBL6990865 | 0.71 | CES2 (0.65) | CES2CES1L3MBTL1SNCA | |
| SCHEMBL5141306 | 0.70 | CES2 (0.48) | CES2CES1NPC1RAB9A | |
| SCHEMBL7612594 | 0.70 | CES2 (0.71) | CES2CES1L3MBTL1SNCANPC1 | |
| SCHEMBL5605898 | 0.70 | CES2 (0.71) | CES2CES1L3MBTL1SNCANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242379-A1 | CURCUMIN ANALOGUES FOR TREATING CANCER | Emory University (US) | 2002-09-25 | — | — | EP | claimed |
| WO-2001040188-A9 | CURCUMIN ANALOGUES FOR TREATING CANCER | UNIV EMORY (US) | 2002-07-25 | — | — | WO | claimed |
| WO-2001040188-A1 | CURCUMIN ANALOGUES FOR TREATING CANCER | EMORY UNIVERSITY (US) | 2001-06-07 | — | — | WO | claimed |