Sugi Predict

Sugi Predict / Compounds / SCHEMBL7537781

SCHEMBL7537781

SCHEMBL7537781

N#Cc1cc(F)c(-n2c(C(F)(F)F)cc(=O)[nH]c2=O)cc1F

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ BCAT2 O15382 15/20 0.45
▸ BCAT1 P54687 15/20 0.45
▸ TRPV4 Q9HBA0 1/20 0.37
▸ MEN1 O00255 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ PGR P06401 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7015287 0.90 BCAT1 (0.41) BCAT2BCAT1TRPV4MEN1POLB
SCHEMBL9023737 0.87 MAPT (0.44) BCAT2BCAT1TRPV4MEN1POLB
SCHEMBL8546322 0.86 BCAT1 (0.50) BCAT2BCAT1
SCHEMBL8600186 0.82 BCAT2 (0.39) BCAT2BCAT1PGR
SCHEMBL8578733 0.81 AR (0.34) BCAT2BCAT1MEN1MAPTKMT2A
SCHEMBL8602347 0.80 BCAT2 (0.39) BCAT2BCAT1PGR
SCHEMBL8422383 0.80 BCAT2 (0.40) BCAT2BCAT1MAPTHSD17B10ALDH1A1
SCHEMBL5922790 0.79 BCAT1 (0.67) BCAT2BCAT1
SCHEMBL8746379 0.79 BCAT2 (0.39) BCAT2BCAT1
SCHEMBL7531189 0.78 BCAT1 (0.59) BCAT2BCAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1192140-A1 SUBSTITUTED HERBICIDAL PHENYLURACILS Bayer Aktiengesellschaft (DE) 2002-04-03 — — EP disclosed
WO-2000078734-A1 SUBSTITUTED HERBICIDAL PHENYLURACILS BAYER AKTIENGESELLSCHAFT (DE) 2000-12-28 — — WO disclosed
EP-1030846-A1 METHOD FOR PRODUCING AR(ALK)YLURACILES, NOVEL CORRESPONDING INTERMEDIATE PRODUCTS AND METHOD FOR PRODUCING SAID INTERMEDIATE PRODUCTS BAYER AG (DE) 2000-08-30 — — EP disclosed
EP-0948482-A2 METHOD FOR PRODUCING TRIFLUOROACETOACETIC ACID ANILIDES BAYER AG (DE) 1999-10-13 — — EP disclosed
EP-0946522-A1 METHOD FOR PRODUCING 1-PHENYL-URACIL DERIVATIVES BAYER AG (DE) 1999-10-06 — — EP disclosed
WO-1999025698-A1 METHOD FOR PRODUCING AR(ALK)YLURACILES, NOVEL CORRESPONDING INTERMEDIATE PRODUCTS AND METHOD FOR PRODUCING SAID INTERMEDIATE PRODUCTS BAYER AKTIENGESELLSCHAFT (DE) 1999-05-27 — — WO disclosed
EP-0880506-A1 PROCESS FOR THE PREPARATION OF SUBSTITUTED CYANOPHENYL URACILS FROM SUBSTITUTED AMINOALKENE ACID CYANOPHENYL AMIDES BAYER AG (DE) 1998-12-02 — — EP disclosed
WO-1998027057-A2 METHOD FOR PRODUCING TRIFLUOROACETOACETIC ACID ANILIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-06-25 — — WO disclosed
WO-1998027067-A1 METHOD FOR PRODUCING 1-PHENYL-URACIL DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1998-06-25 — — WO disclosed
EP-0842155-A1 SUBSTITUTED AMINOURACILS BAYER AG (DE) 1998-05-20 — — EP disclosed
EP-0823899-A1 PROCESS FOR PREPARING SUBSTITUTED ARYLURACILS BAYER AG (DE) 1998-02-18 — — EP disclosed
WO-1997029094-A1 PROCESS FOR THE PREPARATION OF SUBSTITUTED CYANOPHENYL URACILS FROM SUBSTITUTED AMINOALKENE ACID CYANOPHENYL AMIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-08-14 — — WO disclosed
EP-0759908-A1 SUBSTITUTED DIAZACYCLOHEXANDI(THI)ONES BAYER AG (DE) 1997-03-05 — — EP disclosed
EP-0758324-A1 SUBSTITUTED AROMATIC THIOCARBOXYLIC ACID AMIDES AND THEIR USE AS HERBICIDES BAYER AG (DE) 1997-02-19 — — EP disclosed
WO-1997005116-A1 SUBSTITUTED AMINOURACILS BAYER AKTIENGESELLSCHAFT (DE) 1997-02-13 — — WO disclosed
WO-1996034859-A1 PROCESS FOR PREPARING SUBSTITUTED ARYLURACILS BAYER AKTIENGESELLSCHAFT (DE) 1996-11-07 — — WO disclosed
WO-1995031440-A1 SUBSTITUTED DIAZACYCLOHEXANDI(THI)ONES BAYER AKTIENGESELLSCHAFT (DE) 1995-11-23 — — WO disclosed