Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT1 | P54687 | 11/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | USP14 | P54578 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537781 | 0.90 | BCAT2 (0.45) | BCAT1BCAT2ALDH1A1TRPV4MEN1 | |
| SCHEMBL9023737 | 0.78 | MAPT (0.44) | BCAT1BCAT2ALDH1A1TRPV4MEN1 | |
| SCHEMBL8546322 | 0.76 | BCAT1 (0.50) | BCAT1BCAT2 | |
| SCHEMBL5922790 | 0.74 | BCAT1 (0.67) | BCAT1BCAT2 | |
| SCHEMBL7740917 | 0.74 | BCAT1 (0.45) | BCAT1BCAT2ALDH1A1TRPV4PGR | |
| SCHEMBL8600186 | 0.73 | BCAT2 (0.39) | BCAT1BCAT2PGR | |
| SCHEMBL8602347 | 0.72 | BCAT2 (0.39) | BCAT1BCAT2PGR | |
| SCHEMBL8422383 | 0.72 | BCAT2 (0.40) | BCAT1BCAT2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL8420147 | 0.71 | BCAT2 (0.41) | BCAT1BCAT2ALDH1A1 | |
| SCHEMBL8578733 | 0.70 | AR (0.34) | BCAT1BCAT2MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272478-A1 | SUBSTITUTED PHENYLURACILS | Bayer Aktiengesellschaft (DE) | 2003-01-08 | — | — | EP | disclosed |
| EP-1192140-A1 | SUBSTITUTED HERBICIDAL PHENYLURACILS | Bayer Aktiengesellschaft (DE) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001077084-A1 | SUBSTITUTED PHENYLURACILS | BAYER CROPSCIENCE AG (DE) | 2001-10-18 | — | — | WO | disclosed |
| WO-2000078734-A1 | SUBSTITUTED HERBICIDAL PHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |