Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 7/20 | 0.39 |
| ▸ | BCAT1 | P54687 | 7/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537781 | 0.87 | BCAT2 (0.45) | MAPTKMT2AMEN1POLBHSD17B10 | |
| SCHEMBL7696171 | 0.80 | BCAT1 (0.53) | BCAT2BCAT1ALDH1A1KDM4E | |
| SCHEMBL7015287 | 0.78 | BCAT1 (0.41) | MAPTKMT2AMEN1POLBHSD17B10 | |
| SCHEMBL7692441 | 0.74 | BCAT2 (0.39) | BCAT2BCAT1TRPV4 | |
| SCHEMBL8546322 | 0.74 | BCAT1 (0.50) | BCAT2BCAT1 | |
| SCHEMBL9023591 | 0.73 | MAPT (0.43) | MAPTKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL5922790 | 0.72 | BCAT1 (0.67) | BCAT2BCAT1 | |
| SCHEMBL8193759 | 0.71 | BCAT2 (0.40) | BCAT2BCAT1TRPV4 | |
| SCHEMBL8927953 | 0.71 | BCAT2 (0.40) | BCAT2BCAT1TRPV4 | |
| SCHEMBL8600186 | 0.71 | BCAT2 (0.39) | BCAT2BCAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736014-A1 | N-CYANOARYL NITROGEN HETEROCYCLES WITH SULPHUR-CONTAINING GROUPINGS | BAYER AG (DE) | 1996-10-09 | — | — | EP | disclosed |