Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NRP1 | O14786 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537970 | 0.87 | ACLY (0.50) | ACLYHPGDTSHRLMNAGAA | |
| SCHEMBL532975 | 0.84 | ACLY (0.69) | ACLYHPGDTSHRLMNAGAA | |
| Hydrochloric Acid SCHEMBL533067 | 0.83 | ACLY (0.68) | ACLYHPGDTSHRLMNAGAA | |
| SCHEMBL7531860 | 0.82 | LMNA (0.54) | ACLYHPGDTSHRLMNAALDH1A1 | |
| SCHEMBL4569871 | 0.81 | ACLY (0.52) | ACLYTSHRKMT2AHSD17B10MEN1 | |
| SCHEMBL7538874 | 0.81 | METAP2 (0.55) | ACLYHPGDTSHRLMNAGAA | |
| SCHEMBL7537973 | 0.81 | LMNA (0.46) | ACLYHPGDTSHRLMNAGAA | |
| SCHEMBL2747710 | 0.81 | ACLY (0.59) | ACLYHPGDTSHRLMNANPSR1 | |
| SCHEMBL7530812 | 0.79 | CYP2C9 (0.52) | ACLYHPGDTSHRLMNAGAA | |
| SCHEMBL2748413 | 0.79 | ACLY (0.54) | ACLYHPGDTSHRALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |