SCHEMBL7765

SCHEMBL7765

O=COCc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.57
DRD2 P14416 2/20 0.42
DRD4 P21917 2/20 0.42
DRD3 P35462 2/20 0.42
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
HTR7 P34969 1/20 0.38
HTR2B P41595 1/20 0.38
MAOA P21397 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MIF P14174 5/20 0.34
GPR84 Q9NQS5 1/20 0.33
BCHE P06276 1/20 0.33
CES1 P23141 1/20 0.33
MAP3K9 P80192 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2316420 0.85 PNMT (0.54) PNMTDRD2DRD4DRD3NPC1
SCHEMBL7534249 0.85 PNMT (0.54) PNMTDRD2DRD4DRD3NPC1
SCHEMBL5254177 0.81 DRD2 (0.42) PNMTDRD2DRD4DRD3NPC1
SCHEMBL8672207 0.81 PNMT (0.53) PNMTDRD2DRD4DRD3NPC1
SCHEMBL5252581 0.80 PNMT (0.49) PNMTDRD2DRD4DRD3NPC1
SCHEMBL7886099 0.80 PNMT (0.51) PNMTDRD2DRD4DRD3NPC1
SCHEMBL896998 0.79 PNMT (0.54) PNMTDRD2DRD4DRD3NPC1
SCHEMBL3979804 0.79 PNMT (0.67) PNMTDRD2DRD4DRD3NPC1
SCHEMBL7538016 0.79 PNMT (0.62) PNMTDRD2DRD4DRD3NPC1
SCHEMBL123076 0.79 PNMT (0.62) PNMTDRD2DRD4DRD3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 25642 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382496-A1 PROCESSES FOR FORMING CROSSLINKED POLYMER FILMS DUPONT ELECTRONICS INC (US) 2025-12-18 US claimed
US-12404421-B2 Coating solutions and crosslinked polymer films DUPONT ELECTRONICS, INC. (US) 2025-09-02 US claimed
CN-118369094-A Process for preparing substituted pyrazolopyrimidines KSQ治疗公司 2024-07-19 CN claimed
CN-114644568-B Purification method of sitagliptin intermediate 浙江医药股份有限公司新昌制药厂 2024-07-19 CN claimed
US-20240240114-A1 Improved Combination of Protease and Protease Inhibitor with Secondary Enzyme BASF SE (DE) 2024-07-18 US claimed
EP-3634951-B1 NOVEL SUBSTITUTED SULFOXIMINE COMPOUNDS ZYDUS LIFESCIENCES LTD (IN) 2024-07-10 EP claimed
CN-107089993-B Hypolipidemic activity bamboo-cypress lactone compound, preparation method and application thereof 中国科学院上海药物研究所 2024-07-09 CN claimed
CN-111093687-B Use of peptides as therapeutic agents for autoimmune diseases and bone diseases 凯恩塞恩斯株式会社 2024-07-09 CN claimed
CN-111148525-B Use of peptides as therapeutic agents for autoimmune diseases and bone diseases 凯恩塞恩斯株式会社 2024-07-05 CN claimed
CN-113646322-B Solid phase peptide synthesis method and device 奥利弗·约翰内斯·克鲁泽 2024-07-05 CN claimed
US-4732970-A Antitumor amino acid and peptide derivatives of 1,4-bis(aminoalkyl and hydroxy-aminoalkyl)amino)-5,8-dihydroxyanthraquinones AMERICAN CYANAMID COMPANY (US) 1988-03-22 US claimed
US-4725581-A NERVOUS SYSTEM DISORDERS, COGNITION ACTIVATORS ADIR ET COMPAGNIE (FR) 1988-02-16 US claimed
EP-0223143-A2 Analogs of atrial natriuretic peptides CALIFORNIA BIOTECHNOLOGY, INC. (US) 1987-05-27 EP claimed
WO-1987002674-A1 ANALOGS OF ATRIAL NATRIURETIC PEPTIDES BIOTECHNOLOGY RESEARCH ASSOCIATES, J.V. (US) 1987-05-07 WO claimed
EP-0213499-A2 Amino acid derivatives, process for their preparation and use BOEHRINGER INGELHEIM KG (DE) 1987-03-11 EP claimed
EP-0175323-A2 Biologically active peptides, processes for preparing them and pharmaceutical compositions FARMITALIA CARLO ERBA S.r.l. (IT) 1986-03-26 EP claimed
US-4535167-A CONDENSATION OF ACID AND ALDEHYDE FOLLOWED BY REDUCTIVE CLEAVAGE OF OXAZOLIDINONE INTERMEDIATE MERCK & CO. INC. (US) 1985-08-13 US claimed
EP-0010297-B1 DERIVATIVES OF POLYENE MACROLIDE ANTIBIOTICS CONTAINING AN AMINO SUGAR MOIETY, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SCHERING CORPORATION (US) 1983-04-13 EP claimed
US-4232164-A Purification of AT-125 THE UPJOHN COMPANY (US) 1980-11-04 US claimed
EP-0010297-A1 Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them SCHERING CORPORATION (US) 1980-04-30 EP claimed