Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | NAAA | Q02083 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MLYCD | O95822 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | THRA | P10827 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13577935 | 0.98 | HPGD (0.68) | L3MBTL1NAAAHPGDEPHX1SMN1; SMN2 | |
| SCHEMBL104793 | 0.94 | HPGD (0.70) | L3MBTL1NAAAHPGDEPHX1SMN1; SMN2 | |
| SCHEMBL30527282 | 0.88 | L3MBTL1 (0.86) | L3MBTL1NAAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10481026 | 0.88 | L3MBTL1 (0.86) | L3MBTL1NAAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL258708 | 0.88 | L3MBTL1 (0.86) | L3MBTL1NAAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL845966 | 0.88 | L3MBTL1 (0.86) | L3MBTL1NAAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6535660 | 0.88 | L3MBTL1 (0.86) | L3MBTL1NAAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9265536 | 0.88 | L3MBTL1 (0.86) | L3MBTL1NAAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9504178 | 0.88 | L3MBTL1 (0.86) | L3MBTL1NAAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL846047 | 0.88 | L3MBTL1 (0.86) | L3MBTL1NAAASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130259882-A1 | Conjugate of Folate and Antibody Preparation Method and Use Thereof | ZHEJIANG JIANFENG HANSHENG BIOSCIENCES CO., LTD. (CN) | 2013-10-03 | — | — | US | disclosed |
| US-20130259882-A1 | Conjugate of Folate and Antibody Preparation Method and Use Thereof | ZHEJIANG JIANFENG HANSHENG BIOSCIENCES CO., LTD. (CN) | 2013-10-03 | — | — | US | disclosed |
| WO-2012062094-A1 | CONJUGATE OF FOLATE AND ANTIBODY, PREPARATION METHOD AND USE THEREOF | 武汉华耀生物医药有限公司 (CN) | 2012-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130259882-A1 | Conjugate of Folate and Antibody Preparation Method and Use Thereof | FOLR1, FOLR2, DHFR | L3MBTL1 3734/4885NAAA 547/4885HPGD 155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.