SCHEMBL7538259

SCHEMBL7538259

C1=CC2CCC1C2.CC(=O)C(C)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1477532 0.83 TP53 (0.33) POLBAPEX1TDP1
Lactic Acid SCHEMBL27869535 0.81 TP53 (0.50) POLBAPEX1TDP1
Acetic Acid SCHEMBL539228 0.80 POLB (0.40) POLBAPEX1TDP1
Alanine SCHEMBL20659403 0.79 SLC1A2 (0.36) APEX1
D-Alanine SCHEMBL15794269 0.79 SLC1A2 (0.36) APEX1
Bicarbonate SCHEMBL976297 0.75 POLB (0.38) POLBAPEX1TDP1
SCHEMBL5386710 0.75
SCHEMBL79779 0.75
Threonine SCHEMBL20659346 0.73 SLC7A5 (0.40)
SCHEMBL11586811 0.73 REN (0.38) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6476240-B2 POLYMERS DERIVED FROM AN UNSATURATED FUSED CYCLIC HYDROCARBON (SUCH AS PERHYDRO-2,3-DIDEHYDRO-1,4:5,8-DIMETHANONAPHTHALENE) JOINED BY A LINKER TO AN ESTER GROUP HAVING ONE OR TWO PROTECTED HYDROXYLS; USE AS PHOTORESIST WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-05 US disclosed
US-20020042531-A1 Polymers derived from an unsaturated fused cyclic hydrocarbon (such as perhydro-2,3-didehydro-1,4:5,8-dimethanonaphthalene) joined by a linker to an ester group having one or two protected hydroxyls; use as photoresist WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2002-04-11 US disclosed
US-6331602-B1 Monomer and a polymer obtained therefrom WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2001-12-18 US disclosed
US-6160068-A Monomer and a polymer obtained therefrom WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2000-12-12 US disclosed
US-6143472-A Resist composition and a method for formation of a pattern using the composition WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2000-11-07 US disclosed
EP-0918048-A1 A novel monomer and a polymer obtained therefrom Wako Pure Chemical Industries, Ltd. (JP) 1999-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020042531-A1 Polymers derived from an unsaturated fused cyclic hydrocarbon (such as perhydro-2,3-didehydro-1,4:5,8-dimethanonaphthalene) joined by a linker to an ester group having one or two protected hydroxyls; use as photoresist AHR, DHCR24, FPR1 POLB 1463/4885APEX1 17/4885TDP1 1357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.