Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751782 | 0.79 | KMT2A (0.49) | KMT2ACA1CA2CA9POLB | |
| SCHEMBL752888 | 0.79 | KMT2A (0.41) | KMT2APOLBTDP1LMNAIDO1 | |
| SCHEMBL751781 | 0.79 | EGFR (0.40) | KMT2ACA1CA2CA9POLB | |
| SCHEMBL746514 | 0.79 | MEN1 (0.44) | KMT2AALDH1A1IDO1MEN1 | |
| SCHEMBL752330 | 0.79 | LDHA (0.49) | KMT2ACA1CA2CA9POLB | |
| SCHEMBL752209 | 0.79 | LMNA (0.41) | POLBALDH1A1TDP1LMNAGAA | |
| SCHEMBL4400952 | 0.75 | KMT2A (0.62) | KMT2ACA1CA2CA9POLB | |
| SCHEMBL16971268 | 0.75 | KMT2A (0.45) | KMT2ACA1CA2CA9POLB | |
| SCHEMBL788780 | 0.73 | KMT2A (0.50) | KMT2ACA1CA2CA9POLB | |
| SCHEMBL515055 | 0.73 | KMT2A (0.50) | KMT2ACA1CA2CA9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213166-B1 | Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone | THOR GMBH (DE) | 2012-03-21 | — | — | EP | claimed |
| US-20100189811-A1 | Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone | THOR GMBH (DE) | 2010-07-29 | — | — | US | claimed |
| EP-2366554-B1 | Thermosensitive recording medium | RICOH CO LTD (JP) | 2014-04-30 | — | — | EP | disclosed |
| US-8709974-B2 | Thermosensitive recording medium | RICOH COMPANY, LTD. (JP) | 2014-04-29 | — | — | US | disclosed |
| US-8287631-B2 | Compounds for preventing ghost odour | THOR GMBH (DE) | 2012-10-16 | — | — | US | disclosed |
| US-20110230341-A1 | THERMOSENSITIVE RECORDING MEDIUM | RICOH COMPANY, LTD. (JP) | 2011-09-22 | — | — | US | disclosed |
| EP-2366554-A2 | Thermosensitive recording medium | Ricoh Company, Ltd. (JP) | 2011-09-21 | — | — | EP | disclosed |
| US-20100189811-A1 | Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone | THOR GMBH (DE) | 2010-07-29 | — | — | US | disclosed |
| US-20100186631-A1 | Compounds for preventing ghost odour | THOR GMBH (DE) | 2010-07-29 | — | — | US | disclosed |
| US-4018611-A | Non-yellowing antimicrobial compositions comprising diiodomethyl sulfones | METALORGANA ETABLISSEMENT (FL) | 1977-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189811-A1 | Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone | MBTD1, MPST, B2M | KMT2A 2043/4885CA1 3656/4885CA2 1575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.