Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543472 | 0.84 | KDM4E (0.36) | KDM4EADRA2ANISCHPDCD1LG2CD274 | |
| Hydrochloric Acid SCHEMBL8218663 | 0.84 | KDM4E (0.39) | KDM4EADRA2ANISCHPDCD1LG2CD274 | |
| SCHEMBL8218198 | 0.74 | NISCH (0.40) | KDM4EADRA2ANISCHPDCD1LG2CD274 | |
| SCHEMBL8218532 | 0.73 | NISCH (0.38) | KDM4EADRA2AADRA1ANISCHPDCD1LG2 | |
| Iodide SCHEMBL7537909 | 0.71 | NOS3 (0.36) | ADRA2ANISCH | |
| SCHEMBL8198539 | 0.71 | MC4R (0.49) | NISCHPDCD1LG2CD274 | |
| SCHEMBL7485052 | 0.70 | KDM4C (0.37) | RENKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL8208937 | 0.70 | PDCD1LG2 (0.35) | KDM4EPARP1NISCHPDCD1LG2CD274 | |
| Hydrochloric Acid SCHEMBL8203684 | 0.70 | MC4R (0.46) | KDM4ENISCHPDCD1LG2CD274 | |
| SCHEMBL6824821 | 0.69 | MC4R (0.43) | KDM4ENISCHPDCD1LG2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204644-A1 | SYNTHESIS OF SUBSTITUTED AMIDINES | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2000078725-A1 | SYNTHESIS OF SUBSTITUTED AMIDINES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000078724-A2 | IMIDAZOLINDERIVATIVES THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |