Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 7/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8218663 | 0.78 | KDM4E (0.39) | PDCD1LG2CD274NISCHKDM4E | |
| SCHEMBL7543472 | 0.78 | KDM4E (0.36) | PDCD1LG2CD274NISCHKDM4E | |
| SCHEMBL6820927 | 0.76 | NISCH (0.59) | PDCD1LG2CD274NISCHKDM4E | |
| SCHEMBL8194455 | 0.71 | ALDH1A1 (0.35) | KDM4E | |
| Hydrochloric Acid SCHEMBL8204086 | 0.71 | CD274 (0.46) | PDCD1LG2CD274NISCHMC4RKCNH2 | |
| SCHEMBL7538424 | 0.70 | REN (0.33) | PDCD1LG2CD274NISCHPARP1KDM4E | |
| SCHEMBL8195029 | 0.70 | MEN1 (0.43) | PARP1 | |
| SCHEMBL6825218 | 0.70 | KCNH2 (0.43) | PDCD1LG2CD274NISCHMC4RKCNH2 | |
| SCHEMBL8198539 | 0.69 | MC4R (0.49) | PDCD1LG2CD274NISCHMC4RKCNH2 | |
| Hydrochloric Acid SCHEMBL7738758 | 0.69 | KCNH2 (0.43) | PDCD1LG2CD274NISCHMC4RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078724-A2 | IMIDAZOLINDERIVATIVES THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |