Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.33 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.33 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569287 | 0.94 | CTSL (0.41) | CTSLITGB1ITGA4MMP3MMP2 | |
| SCHEMBL7541267 | 0.93 | P2RX7 (0.38) | CTSLALDH1A1KEAP1NFE2L2P2RX7 | |
| SCHEMBL7540853 | 0.93 | CTSL (0.37) | CTSLITGB1ITGA4MMP3MMP2 | |
| SCHEMBL7541924 | 0.92 | ANPEP (0.41) | CTSLCTSSALDH1A1P2RX7KMT2A | |
| SCHEMBL7538662 | 0.92 | GRN (0.40) | GRNSORT1CTSLCTSSALDH1A1 | |
| SCHEMBL7538819 | 0.90 | CTSL (0.36) | CTSLALDH1A1LMNAKMT2AITGB1 | |
| SCHEMBL7541602 | 0.89 | GRN (0.41) | GRNSORT1ALDH1A1LMNAITGB1 | |
| SCHEMBL7540987 | 0.89 | GRN (0.41) | GRNSORT1ALDH1A1LMNAITGB1 | |
| SCHEMBL7568018 | 0.88 | CTSK (0.35) | GRNSORT1CTSLCTSSALDH1A1 | |
| SCHEMBL7566389 | 0.88 | CTSK (0.35) | GRNSORT1CTSLCTSSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |