Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 2/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538679 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MEN1LMNAKMT2ATSHR | |
| SCHEMBL7539918 | 0.92 | MME (0.50) | PPARGADAM17MAOB | |
| SCHEMBL7543915 | 0.92 | MME (0.50) | PPARGADAM17MAOB | |
| SCHEMBL7541085 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MEN1LMNAKMT2ATSHR | |
| SCHEMBL7541086 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MEN1LMNAKMT2ATSHR | |
| SCHEMBL7538549 | 0.75 | YAP1 (0.51) | ALDH1A1MEN1LMNAKMT2ATSHR | |
| SCHEMBL7538553 | 0.75 | YAP1 (0.51) | ALDH1A1MEN1LMNAKMT2ATSHR | |
| SCHEMBL27564126 | 0.73 | ITGB3 (0.55) | ALDH1A1MEN1LMNAKMT2AGAA | |
| SCHEMBL7540882 | 0.72 | MME (0.55) | PPARG | |
| SCHEMBL7540879 | 0.72 | MME (0.55) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |