SCHEMBL753886

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16921587	0.83	KDM4E (0.46)	KDM4ECYP3A4MEN1HPGDKMT2A
	SCHEMBL17922021	0.83	MEN1 (0.62)	KDM4ECYP3A4MEN1HPGDKMT2A
	SCHEMBL16925402	0.81	ALDH1A1 (0.49)	KDM4ECYP3A4MEN1HPGDKMT2A
	SCHEMBL755546	0.81	BCHE (0.44)	KDM4ECYP3A4MEN1HPGDKMT2A
	SCHEMBL4649646	0.80	KDM4E (0.67)	KDM4ECYP3A4MEN1HPGDKMT2A
	SCHEMBL31675988	0.80	KDM4E (0.67)	KDM4ECYP3A4MEN1HPGDKMT2A
	SCHEMBL7660030	0.73	NOX4 (0.76)	KDM4ECYP3A4MEN1HPGDKMT2A
	SCHEMBL15619755	0.72	KDM4E (0.55)	KDM4ECYP3A4MEN1HPGDKMT2A
	SCHEMBL25023089	0.71	MAPT (0.62)	KDM4ECYP3A4MEN1HPGDKMT2A
	SCHEMBL7657022	0.70	KDM4E (0.43)	KDM4ECYP3A4MEN1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.