Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 6/20 | 0.53 |
| ▸ | ACLY | P53396 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538874 | 0.88 | METAP2 (0.55) | METAP2ACLYALDH1A1LMNAKDM4E | |
| SCHEMBL7537970 | 0.81 | ACLY (0.50) | METAP2ACLYALDH1A1LMNAKDM4E | |
| SCHEMBL7538871 | 0.81 | METAP2 (0.53) | METAP2ALDH1A1LMNAKDM4EGAA | |
| SCHEMBL532975 | 0.79 | ACLY (0.69) | METAP2ACLYALDH1A1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL533067 | 0.78 | ACLY (0.68) | METAP2ACLYALDH1A1LMNAKDM4E | |
| SCHEMBL7531857 | 0.77 | POLB (0.52) | METAP2ACLYALDH1A1LMNAKDM4E | |
| SCHEMBL3657767 | 0.76 | ACLY (0.55) | METAP2ACLYLMNAGAANPSR1 | |
| SCHEMBL13316472 | 0.76 | METAP2 (0.60) | METAP2ALDH1A1LMNAKDM4EGAA | |
| SCHEMBL2747681 | 0.74 | ACLY (0.60) | METAP2ACLYALDH1A1LMNAKDM4E | |
| SCHEMBL7537207 | 0.73 | ACLY (0.53) | ACLYLMNAKDM4ENPSR1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |