Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538874 | 0.82 | METAP2 (0.55) | METAP2ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL7538867 | 0.81 | METAP2 (0.53) | METAP2ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL7537973 | 0.80 | LMNA (0.46) | ALDH1A1LMNAGAAHTTMEN1 | |
| SCHEMBL7531707 | 0.79 | RECQL (0.60) | METAP2ALDH1A1LMNAHTTMEN1 | |
| SCHEMBL7532668 | 0.79 | LMNA (0.57) | METAP2ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL7531823 | 0.78 | MAPT (0.55) | ALDH1A1KDM4ELMNAHTTMEN1 | |
| SCHEMBL7569455 | 0.77 | KDM4E (0.67) | ALDH1A1KDM4EGAAHTTMEN1 | |
| SCHEMBL7535073 | 0.76 | MAPT (0.55) | METAP2ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL7531858 | 0.76 | KMT2A (0.55) | ALDH1A1KDM4ELMNAHTTMEN1 | |
| SCHEMBL7537945 | 0.75 | HPGD (0.67) | ALDH1A1KDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |