Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MYOC | Q99972 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546445 | 0.92 | GAA (0.44) | MAPTMMP2MMP1FPR2REN | |
| SCHEMBL7538599 | 0.91 | MMP2 (0.39) | MEN1KMT2ANPSR1MAPTMYOC | |
| SCHEMBL7538603 | 0.91 | MMP2 (0.39) | MEN1KMT2ANPSR1MAPTMYOC | |
| SCHEMBL7569100 | 0.89 | CTSK (0.38) | MEN1KMT2ANPSR1MAPTMYOC | |
| SCHEMBL7538904 | 0.89 | MEN1 (0.48) | MEN1KMT2ANPSR1MAPTMYOC | |
| SCHEMBL7541908 | 0.89 | MEN1 (0.44) | MEN1KMT2ANPSR1MAPTMYOC | |
| SCHEMBL7547224 | 0.89 | SMN1; SMN2 (0.41) | MAPTMMP2HTTFPR2REN | |
| SCHEMBL7541819 | 0.89 | ACE (0.41) | MAPTMMP2MMP1FPR2REN | |
| SCHEMBL7544077 | 0.88 | MAPK1 (0.42) | MAPTMMP2MMP1FPR2REN | |
| SCHEMBL7541665 | 0.87 | MEN1 (0.46) | MEN1KMT2AMMP2MMP1FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |