Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.83 |
| ▸ | MMP1 | P03956 | 19/20 | 0.83 |
| ▸ | MMP9 | P14780 | 19/20 | 0.83 |
| ▸ | ADAM17 | P78536 | 18/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539035 | 0.92 | MMP13 (0.81) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL7006338 | 0.91 | MMP13 (1.00) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL7352698 | 0.87 | MMP13 (0.85) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL7006168 | 0.85 | MMP13 (0.79) | MMP13MMP1MMP9ADAM17 | |
| Hydroxyamine SCHEMBL7381228 | 0.83 | MMP9 (0.60) | MMP13MMP1MMP9ADAM17 | |
| Hydroxyamine SCHEMBL7535068 | 0.81 | MMP1 (0.82) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL27511006 | 0.81 | MMP9 (0.75) | MMP13MMP1MMP9ADAM17 | |
| Hydroxyamine SCHEMBL7473572 | 0.81 | MMP9 (0.83) | MMP13MMP1MMP9ADAM17 | |
| Hydroxyamine SCHEMBL7538525 | 0.81 | MMP9 (0.67) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL7009051 | 0.80 | MMP13 (1.00) | MMP13MMP1MMP9ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998016514-A1 | ORTHO-SULFONAMIDO BICYCLIC HETEROARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |