Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 20/20 | 0.65 |
| ▸ | MMP9 | P14780 | 20/20 | 0.65 |
| ▸ | MMP1 | P03956 | 6/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539094 | 1.00 | MMP2 (0.65) | MMP2MMP9MMP1 | |
| SCHEMBL10021363 | 0.88 | MMP9 (0.74) | MMP2MMP9MMP1 | |
| SCHEMBL7363727 | 0.87 | MMP2 (0.48) | MMP2MMP9MMP1 | |
| SCHEMBL7360556 | 0.86 | MMP2 (0.54) | MMP2MMP9MMP1 | |
| SCHEMBL7360562 | 0.86 | MMP2 (0.54) | MMP2MMP9MMP1 | |
| SCHEMBL8001929 | 0.80 | MMP9 (0.71) | MMP2MMP9MMP1 | |
| SCHEMBL7673474 | 0.79 | MMP2 (1.00) | MMP2MMP9MMP1 | |
| SCHEMBL7673693 | 0.79 | MMP2 (0.83) | MMP2MMP9MMP1 | |
| SCHEMBL7673543 | 0.78 | MMP2 (0.90) | MMP2MMP9MMP1 | |
| SCHEMBL7671031 | 0.78 | MMP2 (1.00) | MMP2MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000044712-A1 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | disclosed |