Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.54 |
| ▸ | MMP9 | P14780 | 11/20 | 0.54 |
| ▸ | MMP3 | P08254 | 2/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 7/20 | 0.49 |
| ▸ | MMP13 | P45452 | 4/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360556 | 1.00 | MMP2 (0.54) | MMP2MMP9MMP3MMP14MMP1 | |
| SCHEMBL7363727 | 0.89 | MMP2 (0.48) | MMP2MMP9MMP14MMP1MMP13 | |
| SCHEMBL7539103 | 0.86 | MMP2 (0.65) | MMP2MMP9MMP1 | |
| SCHEMBL7539094 | 0.86 | MMP2 (0.65) | MMP2MMP9MMP1 | |
| SCHEMBL7924711 | 0.80 | MMP2 (0.63) | MMP2MMP9MMP3MMP14MMP1 | |
| SCHEMBL7922815 | 0.76 | MMP1 (0.59) | MMP2MMP9MMP3MMP14MMP1 | |
| SCHEMBL7922816 | 0.76 | MMP13 (0.48) | MMP2MMP9MMP3MMP14MMP1 | |
| SCHEMBL7447089 | 0.76 | MMP9 (0.58) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL7917022 | 0.75 | MMP2 (0.70) | MMP2MMP9MMP3MMP1 | |
| SCHEMBL7916917 | 0.75 | MMP2 (0.70) | MMP2MMP9MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000044712-A1 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | claimed |
| WO-2000044712-A1 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | disclosed |