SCHEMBL7539540

SCHEMBL7539540

C1=CC2CC1C[C]2Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.39
HSD17B10 Q99714 3/20 0.36
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
TAAR1 Q96RJ0 2/20 0.33
LMNA P02545 1/20 0.33
ADRA2A P08913 1/20 0.33
TSHR P16473 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
ADRA1D P25100 1/20 0.33
ADRA1A P35348 1/20 0.33
ADRA1B P35368 1/20 0.33
LTA4H P09960 2/20 0.32
HPGD P15428 2/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 2/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28298668 0.67 CALM1 (0.50) CALM1TAAR1LMNALTA4HHPGD
Diphenylmethane SCHEMBL28063999 0.64 CALM1 (0.92) CALM1HSD17B10LMNATSHRLTA4H
SCHEMBL14716495 0.61 CALM1 (0.48) CALM1CYP1A2CYP2D6TAAR1LMNA
Diphenylmethane SCHEMBL28172316 0.61 CALM1 (1.00) CALM1HSD17B10LMNATSHRLTA4H
Diphenylmethane SCHEMBL14763944 0.61 CALM1 (1.00) CALM1HSD17B10LMNATSHRLTA4H
Diphenylmethane SCHEMBL3792579 0.61 CALM1 (1.00) CALM1HSD17B10LMNATSHRLTA4H
Diphenylmethane SCHEMBL1303 0.61 CALM1 (1.00) CALM1HSD17B10LMNATSHRLTA4H
Diphenylmethane SCHEMBL4361124 0.61 CALM1 (1.00) CALM1HSD17B10LMNATSHRLTA4H
Diphenylmethane SCHEMBL28072604 0.60 CALM1 (0.80) CALM1LMNALTA4H
Diphenylmethane SCHEMBL25402252 0.59 CALM1 (0.92) CALM1HSD17B10LMNATSHRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6476240-B2 POLYMERS DERIVED FROM AN UNSATURATED FUSED CYCLIC HYDROCARBON (SUCH AS PERHYDRO-2,3-DIDEHYDRO-1,4:5,8-DIMETHANONAPHTHALENE) JOINED BY A LINKER TO AN ESTER GROUP HAVING ONE OR TWO PROTECTED HYDROXYLS; USE AS PHOTORESIST WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-05 US disclosed
US-20020042531-A1 Polymers derived from an unsaturated fused cyclic hydrocarbon (such as perhydro-2,3-didehydro-1,4:5,8-dimethanonaphthalene) joined by a linker to an ester group having one or two protected hydroxyls; use as photoresist WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2002-04-11 US disclosed
US-6331602-B1 Monomer and a polymer obtained therefrom WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2001-12-18 US disclosed
US-6160068-A Monomer and a polymer obtained therefrom WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2000-12-12 US disclosed
EP-0918048-A1 A novel monomer and a polymer obtained therefrom Wako Pure Chemical Industries, Ltd. (JP) 1999-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020042531-A1 Polymers derived from an unsaturated fused cyclic hydrocarbon (such as perhydro-2,3-didehydro-1,4:5,8-dimethanonaphthalene) joined by a linker to an ester group having one or two protected hydroxyls; use as photoresist AHR, DHCR24, FPR1 CALM1 4589/4885HSD17B10 194/4885CYP1A2 625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.