Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484298 | 0.82 | NAMPT (0.36) | GAANAMPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7534680 | 0.81 | NAMPT (0.33) | GAANAMPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7480336 | 0.75 | KDM4E (0.44) | GAAHTTMEN1KMT2ANPC1 | |
| SCHEMBL7480341 | 0.74 | TYK2 (0.36) | GAAPOLBHTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7490200 | 0.74 | KDM4E (0.43) | GAAHTTNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7481351 | 0.73 | TYK2 (0.35) | GAAPOLBHTTMEN1KMT2A | |
| SCHEMBL7481050 | 0.73 | KCNMA1 (0.35) | POLBHTTMEN1KMT2ACYP3A4 | |
| Bromide SCHEMBL7485672 | 0.72 | KCNMA1 (0.35) | POLBHTTMEN1KMT2ACYP3A4 | |
| SCHEMBL7478752 | 0.70 | KCNMA1 (0.39) | POLBMEN1KMT2ARAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7483308 | 0.69 | KCNMA1 (0.38) | POLBMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950056-B1 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |