Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7490200 | 0.99 | KDM4E (0.43) | KDM4EGAATSHRNPC1RAB9A | |
| SCHEMBL7483738 | 0.81 | ACHE (0.40) | KDM4ENCEH1ACHE | |
| SCHEMBL7478752 | 0.81 | KCNMA1 (0.39) | RAB9ASMN1; SMN2TYK2KCNMA1MEN1 | |
| SCHEMBL7480341 | 0.81 | TYK2 (0.36) | GAATYK2KCNMA1HTTMEN1 | |
| Hydrochloric Acid SCHEMBL7483308 | 0.80 | KCNMA1 (0.38) | NPC1RAB9ASMN1; SMN2TYK2KCNMA1 | |
| SCHEMBL7479797 | 0.80 | PKM (0.40) | NCEH1ACHE | |
| SCHEMBL7480188 | 0.80 | KCNH2 (0.35) | KDM4EGAATSHRNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7481351 | 0.80 | TYK2 (0.35) | GAATYK2KCNMA1HTTMEN1 | |
| Hydrochloric Acid SCHEMBL7481921 | 0.79 | KCNH2 (0.34) | KDM4EGAATSHRNPC1RAB9A | |
| SCHEMBL7480200 | 0.76 | ACHE (0.41) | KDM4EACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950056-B1 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |